BayCare is reminding the public about safe practices for handling Thanksgiving leftovers to prevent foodborne illness. The organization highlights that large holiday meals can increase the risk of bacteria growth if food is not stored and reheated properly.
Crystal Thompson, food and nutrition manager at Mease Dunedin Hospital, said, “Foodborne illness peaks around the holidays because we’re often cooking larger quantities and leaving food out longer than usual. With just a few precautions, you can enjoy your leftovers without any unwanted surprises.”
According to the U.S. Department of Agriculture, perishable foods should not be left out for more than two hours. Bacteria multiply quickly between 40°F and 140°F, which experts refer to as the “danger zone.” BayCare recommends using a refrigerator thermometer to ensure temperatures stay below 40°F.
Thompson advised, “Get those leftovers into shallow containers and into the fridge quickly. The faster food cools, the safer it stays.”
Leftovers stored in the refrigerator should be eaten within three to four days. If they will not be consumed in that time frame, freezing is recommended. Most Thanksgiving dishes can be frozen for up to two to six months before quality declines.
“It’s easy to think reheating until it’s hot is enough,” Thompson noted. “But bacteria can survive lukewarm temperatures. Always aim for that 165°F mark when reheating.”
To avoid cross-contamination in the kitchen, BayCare suggests washing hands, utensils and surfaces frequently—especially after handling raw meats or reheating foods—and using separate cutting boards for meat and produce.
Thompson also emphasized caution with spoiled foods: “Your senses are your best defense,” she said, “but safe handling habits matter just as much.” Food that smells off or appears slimy or moldy should be discarded rather than tasted.
For those looking for creative ways to use leftovers, BayCare suggests making turkey sandwiches with cranberry spread and stuffing or preparing turkey pot pie or white bean turkey chili with remaining ingredients from Thanksgiving dinner.
The average American consumes between 3,000 and 4,500 calories on Thanksgiving Day—more than double daily recommendations—so repurposing leftovers into balanced meals may help reduce overconsumption during the holiday weekend.
“Thanksgiving leftovers are meant to be enjoyed, not feared,” Thompson said. “A little planning and attention to safety go a long way in keeping your family healthy through the holidays.”
BayCare Urgent Care offers walk-in services for adults and children six months old and above throughout evenings and weekends for anyone who feels unwell after holiday meals.
Find a location near you: BayCare Urgent Care



